The Center for the Biology of Chronic Disease

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Malu Tansey, PhD

Assistant Professor, Department of Physiology, University of Texas Southwestern Medical School

COMMENTS

Although the book is rather technically difficult due to the large number of mathematical equations it puts forth to substantiate the theory of microcompetition, it is a very thought-provoking read. It gives one an opportunity to think about the relationship between the workings of many biological systems and perhaps the underlying cause of some pathophysiologies. Rather than draw conclusions for the reader, it allows one to draw our own conclusions based on the parts one chooses to accept based on the evidence provided. I found the chapters on autoimmune disease and obesity to be two of the most compelling due to their thoroughness and clarity. Finally, since you specifically asked about my feedback regarding how my work was cited, it was done in an accurate manner.

BIOGRAPHY

Dr. Tansey arrived at U.T. Southwestern after working in the biotech industry in California where she led a multi-disciplinary team of scientists in developing biochemical and cell-based assays to screen computationally designed protein variants for biotherapeutic applications. She conducted postdoctoral studies at U.T. Southwestern and Washington University of St. Louis. At Washington, she was a major contributor to several projects involving GFL action and signal transduction pathways. As a postdoctoral fellow, she has been published in distinguished peer-reviewed journals such as Journal of Neuroscience, Neuron, Journal of Biological Chemistry, and Journal of Cell Biology. Currently, the focus of her laboratory is to investigate the cellular and biochemical mechanisms that regulate RET signal propagation and termination and how alterations in these lead to compromised neuronal survival or transformation.

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