Cervical Dysplasia: Also known as Cervical Interstitial Neoplasia or Cervical Intraepithelial Neoplasia (CIN).
This is a premalignant transformation or abnormal growth on the surface of the cervix. It is not cancer.
In most cases the abnormal growth remains stable, and even eliminated by the immune system.
However, in some cases, if left untreated, it progresses into cervical cancer.
Therefore, most doctors recommend to surgically remove the abnormal growth (see more below).
There are three grades of CIN.
CIN 1: Marks low risk, mild dysplasia, or abnormal cell growth. It is found in the the basal 1/3 of the epithelium.
In most cases it is cleared by immune system in about a year, but it can also take a few years.
CIN 2: Marks medium risk, or moderate dysplasia. It is found in the basal 2/3 of the epithelium.
CIN 3: Marks severe dysplasia. It is found in more than 2/3 of the epithelium. Sometimes it is found in the full thickness of the epithelium.
This growth is also called cervical carcinoma in situ.
The cause of these abnormal growths is the human papillomavirus (HPV). Most of the times, it is caused by the high-risk HPV type 16 and HPV type 18.
What is HPV?
WebMD says "HPV stands for human
papillomavirus, but there are actually more than 100 related viruses
in this group. Each HPV virus is given a number or type. The term
'papilloma' refers to a kind of wart that results from some
HPV lives in the body's epithelial
cells. These are flat and thin cells found on the skin's surface and
also on the surface of the vagina, anus, vulva, cervix, penis head,
mouth, and throat.
Of the 100 HPV types, about 60 types
cause warts on areas such as the hands or feet. The other 40 or so
types of HPV are sexually transmitted and are drawn to the body's
mucous membranes, such as the moist layers around the anal and
genital areas." (1)
How Do You Get HPV?
The CDC says that "HPV is passed on
through genital contact, most often during vaginal and anal sex. HPV
may also be passed on during oral sex and genital-to-genital contact.
HPV can be passed on between straight and same-sex partners - even
when the infected partner has no signs or symptoms.
A person can have HPV even if years
have passed since he or she had sexual contact with an infected
person. Most infected persons do not realize they are infected or
that they are passing the virus on to a sex partner. It is also
possible to get more than one type of HPV.
Very rarely, a pregnant woman with
genital HPV can pass HPV to her baby during delivery. In these cases,
the child can develop recurrent respiratory papillomatosis (RRP), a
rare condition in which warts grow in the throat. In children, this
is also referred to as juvenile-onset recurrent respiratory
papillomatosis (JORRP)." (2)
"About 20 million people in the U.S.
are infected with HPV at any time, according to the CDC. And
three-fourths of sexually active people between ages 15 and 49 have
been infected at some point in their lives, according to estimates
from the American Social Health Association.
You're more likely to get HPV if you:
Have sex at an early age
Have many sex partners
Have a sex partner who has had multiple
How Do You Prevent an HPV Infection?
"The only way to absolutely avoid the
risk of HPV infection is to abstain from sex. You can also limit the
number of sexual partners you have. And you can choose partners
who've had few or no sexual partners before you. However, while a
long-term monogamous relationship lowers your risk, it's important to
remember that many people are infected and never know it." (1)
There are no drugs approved for curing an
infection with the HPV virus. However,
doctors may prescribe a surgical procedure, such as cryotherapy,
conization, and the Loop
Electrosurgical Excision Procedure (LEEP) to remove HPV warts.
In general, these procedures use liquid nitrogen, a surgical knife
(scalpel), a carbon dioxide (CO2) laser, or electrical current to
remove the cells that harbor the active viruses, that is, those viruses
that reside in the warts and cause them to grow. These procedures only
remove the visible symptoms of the HPV infection, that is, the skin or
genital warts. They don't target
the invisible infection, that is, the cells with the latent viruses.
These viruses are left untouched. Since they only
remove the active viruses, they produce a temporary remission, not
a cure. See more on the difference
between remission and cure, here.
If you have visible genital warts, and
would like to learn more about the procedures used to remove them,
visit: WebMD: Genital Wart Removal.
Doctors and health officials may
recommend vaccination with Gardasil (developed by Merck
Pharmaceuticals) or Cervarix (developed by GlaxoSmithKline).
These vaccines aim to prevent a future HPV infection. These
vaccines do not treat cancer, genital warts, or any other symptom of an
HPV infection, and
they do not help individuals who are already infected.
Many doctors may also prescribe a
natural product that was shown to work in published clinical
studies. (3) One such natural product is Gene-Eden-VIR. The
unique feature of this product is that it targets the latent
The CBCD tested the safety and
effectiveness of Gene-Eden-VIR in a post-marketing clinical study.
The study showed that Gene-Eden-VIR decreases symptoms of the HPV virus (and other viruses).
The study was published in the medical journal Pharmacology and Pharmacy,
in a special edition called Advances in Antiviral Drugs
Although it is written in a language suitable for scientists, we urge you to read the full
Gene-Eden-VIR clinical study, see frame below. You can also watch Dr. Hanan Polansky, one of the scientists who conducted the study,
There are two products on the market, Novirin and Gene-Eden-VIR, that have the same five natural ingredients:
100 mg of quercetin, 150 mg of green tea extract, 50 mg of a cinnamon extract, 25 mg of a licorice extract, and 100 mcg of selenium.
The difference between the two products is that Novirin has higher quality, more expensive ingredients.
In recent years, there has been an increase in the demand for natural
remedies, and there is growing evidence that some of these products are
safe and effective. Moreover, natural remedies are a viable option when no other treatments are available,
such as for those already infected with the latent HPV, and for
those wishing to avoid the risks associated with other treatments, and are
willing to wait the extra time it takes for these remedies to
The Center for the Biology of Chronic Disease, or CBCD (see http://www.cbcd.net/)
CBCD is a 501(c)3 not-for-profit organization that specializes in
researching the biology of chronic disease. "The biology of chronic
disease" means the original disruption that causes the disease, and the
sequence of events that lead from the original disruption to the
development of clinical symptoms. The CBCD hopes that once the biology
is clear, pharmaceutical and biotech companies will be able to
formulate drugs that reverse the effects of the disruption, and
therefore cure the disease, or even block the original disruption, and
therefore prevent the disease from developing in healthy individuals.
CBCD conducted the clinical study that tested the safety and
effectiveness of Gene-Eden-VIR.